Disease: Spastic Paraplegia, Hereditary
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZFYVE27 Q5T4F4 zinc finger FYVE-type containing 27 1.1E-09 0.805 0.308
ZFYVE26 Q68DK2 zinc finger FYVE-type containing 26 4.7E-23 0.636 0.615
WASHC5 Q12768 WASH complex subunit 5 Transporter 8.3E-18 0.572 0.615
VCP P55072 valosin containing protein 1.00 0.469 0.923
UCHL1 P09936 ubiquitin C-terminal hydrolase L1 Enzyme 0.99 0.482 0.885
UBQLN2 Q9UHD9 ubiquilin 2 0.85 0.656 0.462
UBAP1 Q9NZ09 ubiquitin associated protein 1 0.91 0.716 0.500
TFG Q92734 trafficking from ER to golgi regulator 0.14 0.595 0.615
TECPR2 O15040 tectonin beta-propeller repeat containing 2 0.58 0.663 0.423
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
SPG21 Q9NZD8 SPG21 abhydrolase domain containing, maspardin 6.6E-04 0.695 0.500
SPG16 spastic paraplegia 16 (complicated, X-linked recessive) 0.722 0.423
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
SPAST Q9UBP0 spastin Cellular structure 1.00 0.579 0.577
SPART Q8N0X7 spartin 3.0E-07 0.588 0.654
SLC33A1 O00400 solute carrier family 33 member 1 Transporter 9.9E-05 0.529 0.769
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
RTN2 O75298 reticulon 2 0.42 0.711 0.385
RNASEH2B Q5TBB1 ribonuclease H2 subunit B 3.3E-09 0.595 0.615
REEP2 Q9BRK0 receptor accessory protein 2 Transporter 0.44 0.792 0.269
REEP1 Q9H902 receptor accessory protein 1 Transporter 0.99 0.653 0.423
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
PRDX5 P30044 peroxiredoxin 5 1.8E-04 0.522 0.808
PNPLA6 Q8IY17 patatin like phospholipase domain containing 6 Enzyme 1.9E-13 0.533 0.769
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769